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PRME · Healthcare

PRIME MEDICINE INC

USA Healthcare Filing: 2025-12-31
Smart-money confidence · 1 of 3 sources firing
Bearish — money moving out

No standout activity across the feeds we track.

Hedge funds
32
Congress
No data
Insiders
No data
Cross-source blend of hedge-fund breadth, Congress trades, and insider Form 4s.  ·  how the score works
◆ Next steps Interested in PRIME MEDICINE INC? Here's what to do with it.
Not financial advice. Bogen Capital surfaces public SEC filings — you decide what to do with them.
Market cap
$544M
Industry
Biotechnology
Sector
Healthcare
Exchange
NasdaqGM
About PRIME MEDICINE INC

Prime Medicine, Inc., a biotechnology company, engages in delivering genetic medicines to address the spectrum of diseases by deploying gene editing technology in the United States. Its lead therapeutic product candidate is PM359 for Chronic Granulomatous Disease, which is in Phase 1/2 clinical trial; PM577 for Wilson Disease, that is in preclinical studies; and PM647 to treat genetic disorder caused by mutations in the SERPINA1 gene, resulting in production of misfolded Z-AAT protein that accumulates in the liver and leads to hepatocellular injury, cirrhosis, and increased risk of…

Who's behind the signal
Every informed buyer we can see on PRME, across all three feeds.
Hedge funds · 6
Point72 (Steve Cohen) New position
D.E. Shaw & Co Decreased −30%
Citadel Advisors Decreased −88%
Congress · 0
No congressional trades on record.
Insiders
No significant Form 4 insider activity in the window.
Not a model pick — but on our radar. PRIME MEDICINE INC isn't in the top-10 model right now, but 6 tracked investors hold it. Everything below is real signal from public filings — treat this as a watch candidate, not a conviction call.
6
Investors
1
New positions
0
Increasing
3
Decreasing
2
Unchanged
Price History
Loading price data...
Return: High: Low:
Who's Holding This Stock
Position sizes and recent activity from tracked institutional investors
Trust weight: 1.1×
New position
% of portfolio
0.0%
Position change
NEW
0.0% of Point72's portfolio
Trust weight: 1.3×
Unchanged
% of portfolio
0.1%
Position change
0.1% of ARK Invest's portfolio
Trust weight: 1.0×
Decreased −30%
% of portfolio
0.0%
Position change
−30%
0.0% of D.E. Shaw & Co's portfolio
Trust weight: 1.0×
Decreased −88%
% of portfolio
0.0%
Position change
−88%
0.0% of Citadel Advisors's portfolio
Trust weight: 1.0×
Unchanged
% of portfolio
0.0%
Position change
0.0% of AQR Capital Management's portfolio
Trust weight: 1.0×
Decreased −96%
% of portfolio
0.0%
Position change
−96%
0.0% of Millennium Management's portfolio
Portfolio Allocation
How much of each investor's portfolio is allocated to PRIME MEDICINE INC
⚠ Disclaimer: This page is for informational purposes only. Holdings data from SEC EDGAR 13F filings, delayed up to 135 days. Not a recommendation to buy or sell PRIME MEDICINE INC or any security.

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